In an experiment using chondrogenic ATDC5 cells, the levels of ALP and calcification, which are factors promoting calcification of cartilage, were significantly decreased in the Collagen peptides group, and the amount of aggrecan, a lubricant for cartilage, was significantly increased.
Reference: Nakatani et al., Osteoarthritis and Cartilage.,17_2009
| AB | Alcian blue stain : stains aggrecan (mucopolysaccharide like chondroitin sulfate and hyaluronic acid). |
| ALP | Alkaline phosphatase stain : identifies a factor involved in the promotion of calcification. |
| AR | Alizarin red stain : an indicator of calcium deposition (calcification). |
