Ingestion of Collagen peptides made the knee joint surface of the femur smooth. In addition, collagen degrading enzyme (MMP-13) and type II collagen degrading marker (CTX-II), which are increased by arthritis, were significantly decreased.

Sham : | Sham-operated |
ACLT : | Anterior cruciate ligament transection |
CP : | Collagen peptide |



Mean±SD, *p<0.05
Reference:Isaka et al., Exp Ther Med.,13_2017